If possible, the relative difference in GIR between women and men is calculated. It appears that a significant part of the H—E clamp studies report a relative higher insulin sensitivity in women when GIR is expressed per kilogram LBM, although not a solely consistent finding. In a few studies, insulin sensitivity has been evaluated directly in skeletal muscle. In a later study by Nuutila et al. Thus, it seems to be a consistent finding that there is a higher glucose uptake in female skeletal muscle when stimulated by physiologic insulin concentrations.
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